Nepalese police fired rubber bullets at thousands of protesters defying a daytime curfew in the capital Katmandu.
At least 23 people were injured in the latest wave of anti-royal protests, according to hospital staff and news reports.
The crowd quickly dispersed after the shooting and the injured were driven to hospital in a UN vehicle, independent TV said. The protests were centred in Katmandu's Kalanki and Gangabu neighbourhoods, while only small groups of protesters were seen in the centre itself.
The curfew was issued after more than 200 people were injured when thousands swept through the city and clashed with security forces. Ignoring a previous order, protesters, opposition leaders and Maoist had rejected King Gyanendra's offer to return to a multiparty democracy.
Opposition alliance leaders said the offer fell short of a key demand - the return of Parliament and election of an assembly to write a constitution. The crisis has escalated since a general strike called by the parties and the Maoists began earlier this month, on April 6.